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Vaccine Quick View: Seasonal/H1N1 Flu (2010/2011)
CSL Limited GlaxoSmithKline MedImmune Novartis Sanofi Pasteur
Afluria Fluarix FluLaval FluMist Agriflu Fluvirin Fluzone Fluzone HD
multi-dose single-dose single-dose multi-dose single-dose single-dose single-dose multi-dose single-dose multi-dose single-dose
INGREDIENT pediatric (6 months thru 3 years) adult (4 years to adult) pediatric (6 months thru 3 years) adult (4 years and older) adult (3 years and older) adult (18 years and older) adult (2 years thru 49 years) adult (18 years and older) adult (4 years and older) adult (4 years and older) pediatric (6 months thru 2 years) adult (3 years and older) pediatric (6 months thru 2 years) adult (3 years and older) adult (65 years and older)
Preservatives
Mercury 12.25 mcg 24.5 mcg 0 0 0 25 mcg 0 0 1 mcg 25 mcg 0 0 12.5 mcg 25 mcg 0
Animal and human DNA/protein
Egg Protein 0.5 mcg 1 mcg 0.5 mcg 1 mcg 0.05 mcg 1 mcg ? 0.4 mcg 1 mcg 1 mcg ? ? ? ? ?
Hydrolyzed Porcine (pig) Gelatin 0 0 0 0 0 0 2 mg 0 0 0 0.125 mg 0.25 mg 0.125 mg 0.25 mg 0.25 mg
Antigens
Influenza A (H1N1) 7.5 mcg 15 mcg 7.5 mcg 15 mcg 15 mcg 15 mcg 15 mcg 15 mcg 15 mcg 15 mcg 7.5 mcg 15 mcg 7.5 mcg 15 mcg 60 mcg
Influenza A (H3N2) 7.5 mcg 15 mcg 7.5 mcg 15 mcg 15 mcg 15 mcg 15 mcg 15 mcg 15 mcg 15 mcg 7.5 mcg 15 mcg 7.5 mcg 15 mcg 60 mcg
Influenza B 7.5 mcg 15 mcg 7.5 mcg 15 mcg 15 mcg 15 mcg 15 mcg 15 mcg 15 mcg 15 mcg 7.5 mcg 15 mcg 7.5 mcg 15 mcg 60 mcg
Antibiotics
Gentamicin Sulfate 0 0 0 0 0.15 mcg 0 0.015 mcg 0 0 0 0 0 0 0 0
Kanamycin 0 0 0 0 0 0 0 0.03 mcg 0 0 0 0 0 0 0
Neomycin Sulfate 0.1 pg 0.2 pg 0.1 pg 0.1 pg 0 0 0 20000 pg (0.02 mcg) 2500000 pg (2.5 mcg) 2500000 pg (2.5 mcg) 0 0 0 0 0
Polymyxin B 0.015 pg 0.03 pg 0.015 pg 0.03 pg 0 0 0 0 3750000 pg (3.75 mcg) 3750000 pg (3.75 mcg) 0 0 0 0 0
Antimicrobial, toxin, or viral inactivators
Formaldehyde 0 0 0 0 5 mcg 25 mcg 0 10 mcg 0 0 50 mcg 100 mcg 50 mcg 100 mcg 100 mcg
beta-Propiolactone 12.5 ng 25 ng 12.5 ng 25 ng 0 0 0 0 500 ng (0.5 mcg) 500 ng (0.5 mcg) 0 0 0 0 0
Sodium Deoxycholate 0 0 0 0 50 mcg 50 mcg 0 0 0 0 0 0 0 0 0
Detergent, emulsifier and dispersing agents, stabilizers
Octoxynol-10 (TRITON X-100) 0 0 0 0 85 mcg 0 0 0 0 0 50 mcg 100 mcg 50 mcg 100 mcg 250 mcg
Polysorbate 80 0 0 0 0 415 mcg 0 0 50 mcg 0 0 0 0 0 0 0
Monosodium Glutamate (MSG) 0 0 0 0 0 0 188 mcg 0 0 0 0 0 0 0 0
Sucrose 0 0 0 0 0 0 13.68 mg 0 0 0 0 0 0 0 0
Vaccine packaging
Latex 0 0 0 0 ? 0 0 ? ? 0 ? ? ? ? ?
Growth medium components
Calcium Chloride 0.75 mcg 1.5 mcg 0.75 mcg 1.5 mcg 0 0 0 0 0 0 0 0 0 0 0
Alpha Tocopheryl Hydrogen Succinate (vitamin E) 0 0 0 0 100 mcg 0 0 0 0 0 0 0 0 0 0
Arginine 0 0 0 0 0 0 2.42 mg 0 0 0 0 0 0 0 0
Hydrocortisone 0 0 0 0 1.6 ng 0 0 0 0 0 0 0 0 0 0
Virus splitter or antigen retrieval
Sodium Taurodeoxycholate 5 ppm 10 ppm 5 ppm 10 ppm 0 0 0 0 0 0 0 0 0 0 0
Cetyl trimethylammonium bromide (CTAB) 0 0 0 0 0 0 0 12 mcg 0 0 0 0 0 0 0
Nonylphenol Ethoxylate 0 0 0 0 0 0 0 0 0.015 % w/v 0.015 % w/v 0 0 0 0 0
Adjust pH, tonicity
Dibasic Potassium Phosphate 0 0 0 0 0 0 2.26 mg 0 0 0 0 0 0 0 0
Dibasic Sodium Phosphate 150 mcg 300 mcg 150 mcg 300 mcg 0 0 0 0 0 0 0 0 0 0 0
Monobasic Potassium Phosphate 10 mcg 20 mcg 10 mcg 20 mcg 0 0 960 mcg 0 0 0 0 0 0 0 0
Monobasic Sodium Phosphate 40 mcg 80 mcg 40 mcg 80 mcg 0 0 0 0 0 0 0 0 0 0 0
Potassium Chloride 10 mcg 20 mcg 10 mcg 20 mcg 0 0 0 0 0 0 0 0 0 0 0
Sodium Chloride 2.05 mcg 4.1 mcg 2.05 mcg 4.1 mcg 0 0 0 0 0 0 ? ? ? ? ?